Everything about ceesdekker

Spatial structure facilitates cooperation inside a social dilemma: empirical evidence from a bacterial community

It was only during the nineties nevertheless, when nanotechnology had State-of-the-art to some stage exactly where solitary molecules could be manipulated, that the 1st experimental devices started to look.

, Groningen scientists present the results of their initiatives to help make labs more sustainable and provide techniques for other labs. 

2007, initial authentic-time detection of strand exchange in homologous recombination by RecA; discovery of a very low persistence length of ends of microtubules; and solved the system of biosensing with carbon nanotubes

2015, discovery that condensin is often a hugely flexible protein composition; and 1st detection of DNA knots utilizing nanopores

The coiled-coil of the human Rad50 DNA maintenance protein is made up of particular segments of amplified versatility

Since 2000 he moved to one-molecule biophysics and nanobiology, with exploration from DNA supercoiling reports of nucleosomes and DNA fix proteins to DNA translocation via nanopores. Recently his investigate has centered on learning cell division with microbes on chip, when his final interest is from the route of recognizing artificial cells.

He also found time to write down several textbooks, mail Practically forty thousand tweets and guide a successful exploration team at Delft University of Know-how. ‘It doesn’t really feel like operate’, he says. ‘I’m just terribly curious.’

In 1993, as a young and eager associate professor at Delft College of Technological know-how, I had at first centered the investigate efforts of my group on measuring the electrical conductance of just one conducting-polymer molecule. Within just two decades, we experienced produced a device through which one wire of the phthalocyaninepolysiloxane polymer was related between two closely spaced metal nanoelectrodes.

Resolving the step size in condensin-pushed DNA loop extrusion identifies ATP binding given that the move-making course of action

‘The idea that There is certainly this type of issue for a commencing, a big bang, is presently an interesting signpost to take into consideration that there was a creator. But extra generally, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: basically, you will discover only atoms and pure forces that we can easily evaluate.

2006, to start with demonstration of molecular sorting inside a lab over a chip applying biomotors; discovery of nanobubbles in solid-state nanopores; and initially estimate of electrokinetic Electrical power conversion inside a nanofluidic channel

Visualization of unstained DNA nanostructures with Superior in-emphasis transmission electron microscopy approaches

Sound-state nanopores have confirmed to become a astonishingly flexible probe for single-molecule analysis of DNA. I will describe many of our the latest conclusions – specially DNA knots – together with our initiatives to grow the capabilities of strong-state nanopores even further more, from the cees dekker course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.